Philip C Amrein Selected Research

Febrile Neutropenia

1/2020

A phase 1 study of the antibody-drug conjugate brentuximab vedotin with re-induction chemotherapy in patients with CD30-expressing relapsed/refractory acute myeloid leukemia.

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Philip C Amrein Research Topics

Disease

17	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020 - 05/2005
12	Neoplasms (Cancer) 02/2020 - 10/2003
4	Philadelphia Chromosome 01/2022 - 05/2011
4	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 02/2020 - 03/2013
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 05/2011
3	Leukemia 01/2020 - 05/2005
3	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 12/2019 - 05/2011
2	Infections 11/2020 - 06/2016
2	Pathologic Complete Response 11/2019 - 05/2005
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 07/2017 - 05/2011
2	Hyperbilirubinemia 08/2016 - 03/2008
2	Carcinoma (Carcinomatosis) 10/2005 - 10/2003
1	Blast Crisis (Blast Phase) 11/2020
1	Anemia 01/2020
1	Thrombocytopenia (Thrombopenia) 01/2020
1	Febrile Neutropenia 01/2020
1	Respiratory Insufficiency (Respiratory Failure) 04/2019
1	Nausea 01/2018
1	Fatigue 01/2018
1	Mucositis 01/2017
1	Cytopenia 01/2017
1	Fever (Fevers) 06/2016
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2014
1	Disease Resistance 04/2014
1	Cardiomyopathies (Cardiomyopathy) 03/2014
1	Leukemic Infiltration 10/2009
1	Hypoxia (Hypoxemia) 03/2008
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 03/2008
1	Salivary Gland Neoplasms (Salivary Gland Cancer) 02/2004
1	Mucoepidermoid Carcinoma 10/2003

Drug/Important Bio-Agent (IBA)

4	Pharmaceutical PreparationsIBA 04/2019 - 10/2009
4	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2018 - 05/2005
3	Lenalidomide (CC 5013)FDA Link 12/2019 - 09/2013
3	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2019 - 11/2012
3	alpha-hydroxyglutarateIBA 01/2019 - 11/2012
3	Bortezomib (Velcade)FDA Link 09/2013 - 03/2008
2	Phosphotransferases (Kinase)IBA 01/2022 - 05/2011
2	Tyrosine Kinase InhibitorsIBA 01/2018 - 07/2017
2	Asparaginase (Elspar)FDA Link 01/2018 - 08/2016
2	Daunorubicin (Cerubidine)FDA LinkGeneric 03/2013 - 05/2005
2	Dasatinib (BMS 354825)FDA Link 05/2011 - 05/2011
2	Trastuzumab (Herceptin)FDA Link 02/2004 - 10/2003
1	Fluconazole (Zonal)FDA LinkGeneric 11/2020
1	Brentuximab VedotinIBA 01/2020
1	larotrectinibIBA 01/2020
1	Immunoconjugates (Immunoconjugate)IBA 01/2020
1	Rituximab (Mabthera)FDA Link 12/2019
1	Bendamustine Hydrochloride FDA Link 12/2019
1	Decitabine FDA Link 04/2019
1	cedazuridineIBA 04/2019
1	decitabine and cedazuridine drug combinationIBA 04/2019
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2018
1	fms-Like Tyrosine Kinase 3IBA 01/2018
1	Glutamine (L-Glutamine)FDA Link 01/2018
1	cabozantinibIBA 01/2018
1	Etoposide (VP 16)FDA LinkGeneric 01/2018
1	ElectrolytesIBA 01/2018
1	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2018
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2018
1	Aurora Kinase AIBA 01/2017
1	MLN 8237IBA 01/2017
1	Imatinib Mesylate (Gleevec)FDA Link 08/2016
1	Biomarkers (Surrogate Marker)IBA 02/2015
1	Core Binding Factors (Core-Binding Factor)IBA 07/2014
1	Biological ProductsIBA 04/2014
1	Gefitinib (Iressa)FDA Link 04/2014
1	Gm(m)IBA 03/2013
1	src-Family KinasesIBA 05/2011
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 03/2008
1	Proteasome InhibitorsIBA 03/2008
1	Proteasome Endopeptidase Complex (Proteasome)IBA 03/2008
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 03/2008
1	Paclitaxel (Taxol)FDA LinkGeneric 10/2005
1	Amifostine (Ethyol)FDA LinkGeneric 10/2005
1	7- cyano- 2,3,4,5- tetrahydro- 1- (1H- imidazol- 4- ylmethyl)- 3- (phenylmethyl)- 4- (2- thienylsulfonyl)- 1H- 1,4- benzodiazepine (BMS 214662)IBA 04/2004
1	Farnesyltranstransferase (Farnesyltransferase)IBA 04/2004
1	ParaffinIBA 02/2004

Therapy/Procedure

13	Therapeutics 11/2020 - 05/2005
8	Drug Therapy (Chemotherapy) 01/2020 - 05/2005
3	Induction Chemotherapy 01/2020 - 03/2008
2	Consolidation Chemotherapy 03/2013 - 07/2011
1	Immunotherapy 01/2020
1	Oral Administration 04/2019
1	Hematopoietic Stem Cell Transplantation 08/2016
1	Transplantation 06/2016
1	Terminal Care (Care, Terminal) 08/2015
1	Remission Induction 03/2013
1	Stem Cell Transplantation 07/2011
1	Radiotherapy 10/2005
1	Intravenous Infusions 04/2004